Similarity Analysis of Protein Sequences Based on the EMD Method

Abstract

An Empirical Mode Decomposition (EMD) method to analyze the similarities of protein sequences is proposed. The EMD method was used to divide a signal sequence converted from a protein sequence into a group of well-behaved Intrinsic Mode Functions (IMFs) and a residue which is monotonic or a trend. This is so that the similarities can be compared among protein sequences by the corresponding residues conveniently and intuitively. This work verifies the method's suitability by using the cytochrome c protein sequences of seven different species.