The Direct Robin Boundary Value Parabolic System of Time-Resolved Diffuse Optical Tomography with Fluorescence

Abstract

We consider a system of parabolic PDEs with measure data modelling a problem of the time resolved diffuse optical tomography with a fluorescence term and Robin boundary conditions. We focus on the direct problem where the quantity of interest is the density of photons in the diffusion equations and which constitutes a major step to solve the inverse problem of identifiability and reconstruction of diffusion, absorption and concentration of the fluorescent markers. We study the problem under a variational form and its discretization with finite element method and we give some numerical simulation results for verification purpose as well as simulations with real data from a tomograph.